For a monoid M and an endomorphism α of a ring R, we introduce the notion of strongly M-α-reflexive rings and study its properties. For an u.p.-monoid M and a right Ore ring R with its classical right quotient ring Q, we prove that R is strongly M-α-reflexive if and only if Q is strongly M-α-reflexive, where R is α-rigid, α is an epimorphism of R. The relationship between some special subrings of upper triangular matrix rings and strongly M-α-reflexive rings is also investigated. Several known results similar to strongly M-α-reversible rings are obtained.